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The Restless Legs Syndrome Webcyclopedia @ Leg Pain Guide

This section @ the Leg Pain Guide is about Restless Legs Syndrome.

The RLS Webcyclopedia provides one of the most comprehensive set of high quality web resources for those seeking information on latest treatment or research into RLS. 

In addition to focussing on links that provides basic inputs and the conventional treatments for Restless Legs Syndrome, this page also places significant emphasis on updates for unique treatments, as well as the latest in treatment methods for Restless Legs Syndrome. 

We hope you benefit from this page.

Restless legs syndromefrom the Leg Pain Guide

Restless legs syndrome is a neuropathic disorder.

People with restless legs syndrome have uncomfortable sensations in their legs (and sometimes arms or other parts of the body) and an irresistible urge to move their legs to relieve the sensations. These problems commonly happen during night, when the person is sleeping or lying down.

This is an ailment that causes significant pain and in addition sleepless nights to millions; and one of the most complex ailments for which no cure has been found (as of 2020). However, a number of treatments have been evolving that try to mitigate and reduce the pain from RLS for the patients.

Over here, we provide a comprehensive set of useful web resources that answer the following questions about Restless Leg Syndrome:

  • What is restless legs syndrome?
  • What are the main symptoms for restless legs syndrome?
  • What are the reasons behind restless legs syndrome?
  • What are the main treatments & medications for restless legs syndrome?
  • Videos, communities, FAQs and other resources for restless leg syndrome

The guide is categorized for the following stakeholders:

  • Patients / those seeking treatment or cure
  • Doctors & medical industry, including medical equipment industry

The above categorization does not imply that the categories will benefit ONLY specified by the category name; it is more a prioritization as this portal provides hundreds of resources, so some categorization brings order.

If you wish to know all about restless legs syndrome, we welcome you to use all the sections – over a period of time of course, as it is a lot content over here!


Restless legs syndrome causes & reasons 

What causes RLS? While we do not have ALL the answers yet, medical researchers have been able to figure out in the last decade that it has a lot to do with poor or misplaced signals from the brain to move the limbs when the limbs are actually not ready to move. Kind of a mix up.

What is also fairly established is that RLS is genetic an hereditary – so, it runs in families. Some of the latest researches have even identified the set of genes responsible for RLS.

So, RLS is an ailment owing to misplaced brain signals, and it is most likely hereditary. This much the medical community knows. But why exactly the brain misfires at times is not known, at least as of 2020, making RLS one of those illnesses that has to be categorized under “No cure yet”.

But that does not mean there are no treatments to reduce the pain from this ailment. A range of treatments – both drug-based and natural – are being used with varying success.

In this section, know more about the causes and reasons for RLS from a wide variety of expert sources below:

It’s got to do with your brain

  • Restless legs syndrome – symptoms & causes – A good synopsis of RLS from Mayo Clinic – Read More
  • Mixed signals to blame for restless legs syndrome (2004 study) — Iron-deficient cells in the brain are mixing up central nervous system signals to the legs and arms causing the irresistible urges to move and creepy-crawly sensations that characterize restless legs syndrome (RLS), a Penn State College of Medicine study reports. ScienceDaily –  Read More
  • Restless legs syndrome, insomnia and brain chemistry: A tangled mystery solved? — A small new study (2013), headed by Richard P. Allen, Ph.D., an associate professor of neurology at the Johns Hopkins University School of Medicine, used MRI to image the brain and found glutamate — a neurotransmitter involved in arousal — in abnormally high levels in people with RLS. The more glutamate the researchers found in the brains of those with RLS, the worse their sleep. The findings are published in the May issue of the journal Neurology. “We may have solved the mystery of why getting rid of patients’ urge to move their legs doesn’t improve their sleep,” Allen says. “We may have been looking at the wrong thing all along, or we may find that both dopamine and glutamate pathways play a role in RLS.” – ScienceDaily –   Read More
  • Restless legs syndrome linked to changes in sensory cortex – A new study looking at neural mechanisms involved in restless legs syndrome has come up with some surprising findings — that the condition seems to be related to changes in the sensory rather than the motor area of the brain. Read More
  • How the brain kick starts restless legs at night – This new study (2018), which appears in Sleep Medicine, supports the idea that the underlying mechanism for RLS rests in the brain’s “move my legs” center, researchers say, and makes even more sense of the relief those with RLS experience when they get up and move them. “Essentially, the brain sends the signal when it’s preparing to move a limb, even when you aren’t planning to move, so your body is ready and amped up,” says Richard Allen, professor of neurology at Johns Hopkins School of Medicine. “The only way to alleviate the feeling is to move.” – Futurity –  Read More
  • Restless legs syndrome: new evidence of peripheral mechanism – The study, published in the May 27, 2014 issue of Neurology, found a strong correlation between RLS symptoms and peripheral hypoxia. In addition, the hypoxia was reversed with the initiation of dopaminergic treatment, which also relieved symptoms – Read More

Genetic causes of RLS

  • Researchers discover gene responsible for restless legs syndrome (2007) – An international team of researchers has identified the first gene associated with Restless Legs Syndrome (RLS). The work was led by scientists at Emory University and deCODE Genetics, Inc., in Reykjavik, Iceland. The researchers report a population-attributable risk for RLS of at least 50 percent, meaning that were the gene variant not present, more than half of all RLS cases would disappear. The variant is very common–nearly 65 percent of the population carries at least one copy of the variant. Two copies of the variant more than doubles one’s risk of experiencing RLS – ScienceDaily –  Read More
  • Study gives hints about genetic causes of restless legs syndrome – An international team led by the Technical University of Munich (TUM) and the Helmholtz Center has carried out a large genome-wide association study (year 2017) on the genetic causes of restless legs syndrome (RLS). They discovered 13 new genetic risk variants and identified underlying candidate biological processes. The researchers also investigated the biological processes that are most likely associated with the risk variants and made a surprising discovery: They found that genes involved in the embryonic development of the nervous system are mainly involved—despite the fact that the condition usually manifests itself decades later.- Sleep Review-  Read More
  • Here’s the question to Mayo Clinic: Is restless legs syndrome hereditary? Is there an effective treatment, or does a diagnosis of RLS mean I will have it for life? – Read the detailed answer  from Mayo Clinic here –  Read More
  • New Genes Linked to Restless Legs Syndrome – The study narrowed the results to six genetic regions associated with an increased risk of developing restless legs syndrome. Four of these mutations have been previously reported, and two are new. One of the newly identified genetic regions, TOX3, is involved in regulating brain activity. Previous studies have shown that increased levels of the TOX3 protein protects brain cells from cell death, but the link between TOX3 and restless legs syndrome is not clear. Read More
  • The protein profile of restless leg syndrome – Comparing the cerebral spinal fluid (CSF) of women with and without RLS, researchers from the US and Korea discovered there was a significantly altered level of six specific proteins with RLS. The doctor who led this study explained, “Our results reveal a protein profile in the RLS/WED CSF that is consistent with iron deficiency, dopamine dysregulation and inflammation.” ScienceDaily –  Read More
  • Does Restless Legs Syndrome keep you awake at night? Blame your mum | Daily Mail Online –  The condition has a strong genetic streak: if you have RLS, the chances are a sibling or parent will too.  Read More

Other causes

  • Why do your legs feel restless? — BDN Maine –  Interesting perspectives from Dr. Michael Noonan
    • When treating patients with RLS, I find it helpful not to think of it as a specific diagnosis but as a symptom. This symptom can have many causes, even if the patients all describe very similar complaints. For some patients, the problem is found in the leg muscles themselves. For others, it may reflect imbalances in their brain chemistry, an iron deficiency or a drug reaction.
    • When examining a patient with RLS, I also ask if they started taking a statin drug such as Lipitor, Crestor or Zocor before it started. Leg complaints are a very common side effect of these cholesterol-lowering drugs; up to 75 percent of patients taking a statin have muscle pain as a side effect.
    • Of course, there are natural alternatives for RLS. If it’s because of iron deficiency, the patient often requires not only supplements but also help with digestion — iron can only be absorbed in a normally acidic stomach. Using antacids or drugs to reduce stomach acid interferes with iron uptake and can lead to problems such as anemia or RLS.
    • I have found acupuncture to be helpful in most RLS cases, regardless of the cause.
    • Read More

RLS Diagnosis

  • How does a medical doctor diagnose RLS? –  Read More
  • The best diagnostic procedure for RLS in adults – from NIH – Read More
  • Restless Legs Syndrome diagnosis & treatment – Read More
  • Restless Legs Syndrome – from National Sleep Foundation – Read More
  • Restless Legs Syndrome fact sheet – Read More
  • Differential diagnosis and treatment of RLS: a literature review – Patients with RLS are routinely misdiagnosed and continue their lives without proper management. This literature review examines the current understanding of the disorder, provides key points to assist clinicians in differentiating RLS from similar disorders, and explores recently updated evidence-based guidelines for the effective management of RLS –  Read More
  • Restless legs syndrome – Diagnosis and treatment – Mayo Clinic –  Read More

Restless Legs Syndrome (RLS) Treatments

Breakthroughs in Restless Leg Syndrome Treatment

  • New treatment discovered for Restless Legs Syndrome improves sleep –  Read More
  • Breakthrough in treatment of restless legs syndrome — ScienceDaily –  New research published in the Journal of Physiology presents a breakthrough in the treatment of Restless Legs Syndrome (RLS). Until now it was thought that RLS is caused by genetic, metabolic and central nervous system mechanisms. For the first time the researchers show that, in fact, it is not only the central nervous system but also the nerve cells targeting the muscles themselves that are responsible. This new research indicates that the involuntary leg movements in RLS are caused by increased excitability of the nerve cells that supply the muscles in the leg, which results in an increased number of signals being sent between nerve cells. Targeting the way messages are sent between nerve cells to reduce the number of messages to normal levels may help prevent the symptoms of RLS occurring. This could be achieved by new drugs that block the ion channels that are essential for the communication between nerve cells. Read More
  • New Treatment Option for Restless Leg Syndrome – Apollo by Pivotal Health Solutions –   Read More
  • Research may lead to new treatments for Restless Legs Syndrome –  Read More
  • Breakthrough in treatment of restless legs syndrome — ScienceDaily –  Read More
  • Breakthrough in treatment of restless legs syndrome | EurekAlert! Science News –  Read More
  • Restless legs syndrome brain stimulation study supports motor cortex ‘excitability’ as a cause: Experiments with patients suggest brain stimulation may be a viable treatment — ScienceDaily –  Read More
  • Breakthrough research suggests a potential treatment for restless leg syndrome – Medical News Bulletin | Health News and Medical Research –  Read More
  • medi USA launches new drug-free treatment for Restless Legs Syndrome (RLS) –  Read More
  • Restless Legs Syndrome: New Treatment Improves Sleep — ScienceDaily –  Read More
  • A new, effective treatment for Restless Leg Syndrome: Orgasm | Discover Magazine –  Read More
  • Restless Legs Syndrome: From pathophysiology to clinical diagnosis and management | Frontiers in Aging Neuroscience –  Read More

Drug-based treatments for RLS

  • Medications – Restless Legs Syndrome Foundation –  While there are many non-drug therapies that can help relieve symptoms of restless legs syndrome (RLS), medications may be an important part of the treatment strategy for individuals experiencing frequent or severe symptoms. If you need to take medication, your physician will work with you through careful trials to find a drug and dosage that works best to manage your symptoms. The U.S. Food and Drug Administration (FDA) has approved four drugs for treating RLS, and this page provides more details on these drugs – Read More
  • Diagnosis and novel treatment approaches in restless legs syndrome: II. Treatment. – PubMed – NCBI –  The symptoms of restless legs syndrome (RLS) can be managed effectively by treatment. The pathophysiology of primary RLS is only partly understood; however, a strong association with brain iron deficiency, which possibly impairs dopaminergic function, has been identified. Dopamine agonists are the mainstay of RLS treatment, but other therapies, including gabapentin, benzodiazepines, and low-potency opioids, are also commonly employed. In this review, the focus is on the pathophysiology, comorbidity, differential diagnosis, and novel treatment approaches of RLS – Read More
  • Pramipexole (dopamine agonist) vs. pregabalin (an opioid) for RLS – The Johns Hopkins Center for Restless Legs Syndrome –  This resource presents the summary of a study which is perhaps the first clinically meaningful and methodologically excellent randomized trial of its kind in RLS history. It uses an approach, which truly allows a comparison between a “Goliath” in the RLS treatment armament (pramipexole) and an underappreciated “David” (pregabalin) – Read More
  • Restless Legs Syndrome (RLS) Treatment | National Sleep –   Read More

Non-drug treatments for RLS

  • A simple set of stretches that could bring relief to your nerve pain – an excellent demo through a video by Dr. Silvester
  • 10 natural sleep aids – Psychology Today Canada – The list suggested includes: CBD (cannabidiol), melatonin, magnesium, valerian & hops, magnolia bark, jujube, L-theanine, 5-Hydroxytryptophan (5-HTP), Glycine (also known as 2-Aminoacetic Acid) – Read More
  • Non-pharmacologic interventions for Restless Legs Syndrome Management – Sleep Review –  An interesting overview of many non-pharma interventions. Details provided on the benefits to RLS patients from exercise & physical activities, diet, practice of sleep hygiene, non-pharma compression devices such as Restiffic and Relaxis, others such as iron supplements, hot/cold baths, massages, electrical stimulation, mental activity, use of near-infrared light, and use of vasodilator. Read More
  • Are you missing this simple treatment for restless legs? – Harvard Health – Iron supplementation may be all it takes to reduce symptoms of restless legs syndrome. But many doctors don’t know about it. “The concern is that people are being started on medications first when iron might be a valuable treatment. It’s simple, with relatively few side effects,” says Dr. John Winkelman, an RLS specialist at Harvard-affiliated Massachusetts General Hospital. Read More
  • Restless Legs Syndrome: 16 natural remedies and treatment for RLS – Quite a comprehensive list, includes ideas on: managing your bed timings, stretching workouts, (non) use of caffeine, relaxing baths, applying heat or cold, physical activity, keeping your mind occupied, being in motion, stress reduction techniques including deep breathing, massage, yoga, sleep hygiene (for instance, blue light is bad!), avoiding smoking and alcohol, checking for iron deficiency, checking your other medications for RLS triggers. A very useful checklist indeed.  Read More
  • Easy and simple natural cure for restless leg syndrome – Times of Oman –  A concise list of what to use and consume, and what to eliminate and avoid. Some interesting/unique points:
    • Medications such as allergy pills and cold medications contain mild stimulants which can cause jittery legs
    • You can even use a body massage vibrator which is very helpful in relaxing your leg muscles.
    • Change from cold to hot, or hot to cold can be effective in treating restless leg syndrome.
    • Deficiency of magnesium, folate or iron can cause restless leg syndrome.
    • Wearing socks at bedtime might work for some
    • Add garlic, ginkgo bilboa and hawthorn berries into your diet. They will help in improving your blood circulation.
    • Daily dose of juice like spinach, asparagus or kale juice, are all rich in folate which will help keeping your legs still at night.
    • Read More
  • 10 myths about living with Restless Legs Syndrome | HealthCentral – an excellent list of 10 myths that will be useful to most anyone with RLS – Read More
  • How to get rid of restless legs: Six ways to relieve the uncomfortable leg sensation | –  a detailed news report with useful images and illustrations – Read More
  • 6 ways to beat restless legs | GoodtoKnow –  two interesting ways from among the six mentioned: 1. Take a hot or cold bath before you go to bed, and 2. Eat bananas. Read More
Essential oils for RLS
  • The use of essential oils for sleep by Norma G. Cuellar, PhD –  This is an excerpt from the fall 2016 edition of NightWalkers, the Restless Leg Foundation’s quarterly magazine. Discusses the effects of following oils: lavender, bergamot, vetiver, sandalwood, Roman chamomile, marjoram, Ylang Ylang, and cedarwood – Read More
  • 17 essential oils for Restless Legs Syndrome – from UPNature –  useful info provided on the use of the following oils: Peppermint, lavender, marjoram, vetiver, lemongrass, Roman Chamomile, Frankincense, ginger, jasmine, rosemary, black pepper, basil, bergamot, clove, yarrow,  Read More
  • Goodbye Restless Legs Syndrome essential oil blend – Serum contains the essential oils of vetiver and sandalwood which were selected for their unique sedative properties and ability to calm and relax muscles. They’ve been infused with a superior Omega 9 carrier oil. order from Amazon – Link
Massage therapy, acupuncture for Restless legs syndrome
  • Treat Restless Leg Syndrome pain & stress with massage therapy –  Read More
  • 5 massage tips for Restless Legs Syndrome | Massage Professionals Update –  Read More
  • Massage Treatments for Restless Leg Syndrome – YouTube –   Read More
  • Brazilian consensus on guidelines for diagnosis and treatment for restless legs syndrome –   Read More
  • Dr Physio (USA) electric air compression blood circulation machine leg calf foot massagers for body pain relief massager (Black): Health & Personal Care –  Read More
  • restless leg: Health & Personal Care –  Read More
  • How to manage restless leg syndrome –  Read More
  • Deep Tissue Massage: Benefits, what to expect, and side effects –  Read More
  • Tissue density restoration massage for Restless Legs Syndrome – Read More
Acupuncture & RLS
  • Acupuncture and herbs relieve Restless Leg Syndrome (RLS) –  Read More
  • Pressure points for Restless Leg Syndrome | Acupressure treatment, Restless leg remedies, Restless leg syndrome –   Read More
  • Acupressure massage for Restless Leg Syndrome – HerbalShop –  Read More
  • Acupuncture point injection markedly improved sensory symptoms and motor signs in 2 patients with restless legs syndrome-  Read More
  • The 11 best treatments for Restless Legs Syndrome –  Read More
  • Actigraph evaluation of acupuncture for treating Restless Legs Syndrome –  Read More
  • Acupressure slippers’ health benefits: Do acupressure slippers work? –  Read More
  • Acupuncture point injection markedly improved sensory symptoms and motor signs in 2 patients with restless legs syndrome – The acuinjections at acupuncture points (GB41, BL60, ST36, and SP6) provide immediate relief of sensory symptoms and motor signs of restless legs symptom (RLS). An acuinjection can be promising and safe alternative treatment for pharmacotherapy in patients of RLS. (Images also provided for guidance) – Read More

Restless legs syndrome (RLS) products & treatment equipment for purchase

  • Vectora Accupressure Paduka | Leg Foot Massager | Accupressure Foot Slipers for Both Men And Women – Amazon –  Read More
  • Widecare air compression leg wrap massager enhancing boot wraps using pressure massage to improve circulation, soothes sore muscles: Amazon –  Read More
  • Leg massager for blood circulation air compression with rechargeable battery and cordless – Amazon –  Read More
  • Zurato foot massager machine for pain relief professional – Blood circulation machine/leg, foot and hand massager belt – Amazon –  Read More
  • Unistar unisex acupressure slippers – Amazon –  Read More
  • Varco leg care therapeutic phyto herbal massage oil | Pain relief muscle relaxant – Amazon –  Read More
  • Seven+Minerals Restless Legs Syndrome treatment & cramp pain relief magnesium chloride oil spray – Amazon –  Read More
  • Electric air compression blood circulation machine leg calf foot massagers for body pain relief: Amazon –  Read More

Restless legs syndrome treatment and management – other resources

  • 9 Lifestyle habits to manage RLS – RLS Center – Everyday Health –  Read More
  • Steps to relaxing your restless legs – Dr. Ellie Cannon – Read More
  • A doctor offers health advice for people with restless legs | –   Read More
  • How to manage restless leg syndrome –  Read More
  • How to manage restless leg syndrome – The Morning Call –  Read More
  • First AAN Guideline on Restless Legs Syndrome –  Read More
  • When sleeplessness starts in the legs – Harvard Health –  Read More
  • Getting a leg up on physical therapy – Innovate Long Island –  Read More
  • Practice guidelines: Restless Legs Syndrome – Neurology Advisor –  Read More

Tips for better sleep for those with RLS

  • Tips for better sleep for RLS Sufferers | Healthline –  Read More
  • Weighted blankets: How they work, and why you should get one – CNET –  Read More
  • Treating restless legs syndrome in the context of sleep disordered breathing comorbidity | European Respiratory Society –  Read More
  • RLS Remedies: Home care for better sleep –  Read More

Restless legs syndrome perspectives & opinions

  • How the brain kickstarts restless legs at night – Futurity –  Read More
  • Restless Legs: Why behavioral issues may be linked to your child’s sleep – Health News – 13 WTHR Indianapolis –  Read More
  • Restless Legs Syndrome (RLS) — The patients’ perspective –  Read More
  • My restless legs were like bees biting under my skin’ – BBC News –  Read More
  • – ‘It’s a hugely ridiculed condition, it feels like insects crawling inside your legs’ –  Read More
  • Weighing in on Weighted Blankets: My Experience –  Read More
  • Restless Leg Syndrome and Nerve Cells –  Read More
  • Restless Legs Syndrome: clinical implications for psychiatrists | Psychiatric Times-  Read More
  • Patient Voices: Restless Leg Syndrome – The New York Times –  Read More

Restless legs syndrome (RLS) videos

  • 15 remedies for restless legs syndrome (natural) – Part 1 | animated video – YouTube –  Read More
  • New solutions for restless leg syndrome – YouTube –  Read More
  • RLS and augmentation – YouTube –  Read More
  • What can relieve restless legs syndrome? | In Good Shape – YouTube –  Read More
  • Restless Leg Syndrome can be healed with daily practice of Yoga –  explained by Bharathji! – YouTube – Read More
  • Magnesium, restless legs and your heart – YouTube –  Read More
  • Raleigh acupuncture best treatment for restless leg syndrome – YouTube –  Read More
  • Restless leg syndrome with a general surgeon – YouTube –  Read More
  • Acupuncture case of restless leg syndrome. – YouTube –  Read More
  • Restless Legs Syndrome – The Nebraska Medical Center – YouTube –  Read More
  • Restless legs syndrome cure – YouTube –  Read More
  • Restless legs syndrome – Non-drug solution – YouTube –  Read More
  • How to treat restless legs syndrome: massage treatments for restless legs syndrome – YouTube –  Read More
  • Restless leg syndrome evidence based treatment – YouTube –  Read More
  • A new solution for restless legs syndrome – YouTube –  Read More
  • Yoga poses for restless legs – YouTube –  Read More
  • Acupuncture for restless legs syndrome – YouTube –  Read More
  • What can relieve restless legs syndrome? | In Good Shape – YouTube –  Read More
  • How to treat restless legs syndrome (RLS) – YouTube –  Read More
  • Restless legs syndrome relief (RLS) – Ask Doctor Jo – YouTube –  Read More
  • Relieving restless legs syndrome – YouTube –  Read More

Restless legs syndrome books & guides

  • Restless Legs Syndrome: Relief and Hope for Sleepless Victims of a Hidden Epidemic Book Online – Amazon –  Read More
  • Restless Leg Syndrome :Necessary Precautions & Possible Solutions: (French Edition) eBook: Julie Marsh: Kindle Store –  Read More
  • Restless Legs Syndrome: ‘an Inside Story’ Book Online  – Amazon –  Read More
  • Restless Legs Syndrome: Natural Remedies to Cure RLS and Regain a Healthy Sleeping Cycle – eBook: Chad Warwick: Amazon –  Read More
  • Restless Legs Syndrome: Coping with Your Sleepless Nights (American Academy of Neurology) – Amazon –  Read More
  • Restless Legs Syndrome/Willis Ekbom Disease: Long-Term Consequences and Management Book Online –   Read More


Drugs for restless legs syndrome

  • A medication dosage adjustment has helped to relieve my Restless Legs –  Read More
  • Parkinson’s drug could treat restless leg syndrome, study suggests — ScienceDaily –  Read More
  • FDA approves new Restless Legs Syndrome Drug Horizant –  Read More
  • Opioids prove effective for Restless Legs Syndrome –  Read More
  • Pregabalin effectively treats restless leg syndrome with less risk of worsening symptoms, study finds — ScienceDaily –   Read More
  • 4 precautions to take when prescribing Opioids for refractory Restless Legs Syndrome [Podcast] – Sleep Review –   Read More
  • FDA warns of breathing risks with popular nerve drugs –  Read More
  • Common allergy medication worsens restless leg symptoms — ScienceDaily –  Read More
  • RLS treatment 2019: three orally administered drugs currently in pipeline –  Read More
  • Chronic Opioids and Sleep: what prescribers need to know | MedPage Today –  Read More
  • Guidelines for the first-line treatment of restless legs syndrome/Willis–Ekbom disease, prevention and treatment of dopaminergic augmentation: a combined task force of the IRLSSG, EURLSSG, and the RLS-foundation – ScienceDirect –  Read More
  • Challenges and side effects of RLS drugs:
    • Restless legs episode triggered by common antihistamine | A case where PM (pain medications) containing diphenhydramine was aggravating RLS. This brief case history points to a much larger issue of how various drugs (at least some of the most common and frequently used ones) taken for other diseases and illnesses could affect RLS. Detailed study on this aspect and publication of results could be quite valuable.| –  Read More

Unique treatments for restless legs syndrome

  • Is cannabis an effective treatment for Restless Leg Syndrome? – The GrowthOp –  Read More
  • Masturbation calms restless leg syndrome – now, now… | New Scientist –  Read More
  • Liquid soap cured painful leg spasms –  Read More
  • Marijuana Can Stop Restless Leg Syndrome –  Read More
  • Singer Daniel O’Donnell reveals quirky soap trick he uses to calm his restless legs in bed – could something like this could really work? –  Read More
    • A related soap trick – This is how a bar of soap can help you get a better night’s sleep – really? –  Read More
  • Could the misery of restless legs be relieved with a simple foot wrap? –  Read More

Restless legs syndrome & its connection to other disorders

  • Association between restless legs syndrome and other movement disorders – Neurology Advisor –  Read More
  • The link between restless legs & chronic back pain –  Read More
  • High rate of restless legs syndrome found in adults with fibromyalgia — ScienceDaily –  Read More
  • GERD, restless legs syndrome and migraines –  Read More
  • When sleeplessness starts in the legs – Harvard Health –  Read More
  • Restless legs linked to broken hearts – Harvard Health Blog – Harvard Health Publishing –  Read More
  • Restless legs syndrome may raise high blood pressure risk in middle-aged women — ScienceDaily-   Read More
  • The link between restless legs & chronic back pain –  Read More
  • ScienceDaily –  Read More
  • Restless legs syndrome could be an early sign of a seizure | Epilepsy Research UK –  Read More
  • People with Parkinson’s disease more likely to have leg restlessness than restless leg syndrome –  Read More
  • Restless legs syndrome linked to psychiatric conditions — ScienceDaily –  Read More
  • Study ties restless legs syndrome to heart, kidney problems: Research draws on database of 3 million Veterans –  Read More
  • Restless legs syndrome may signify bigger health problems — ScienceDaily –  Read More
  • Study finds high rates of small intestinal bacterial overgrowth in patients with restless legs syndrome | News-Medical-  Read More
  • Association between restless legs syndrome and other movement disorders – Neurology Advisor-  Read More
  • Restless legs and tinnitus | –  Read More
  • Mayo Clinic finds restless legs syndrome in children linked to family history, iron deficiency — ScienceDaily –   Read More
  • Persistent imminent orgasms in women are associated with restless legs — ScienceDaily –  Read More
  • Restless legs syndrome linked to erectile dysfunction in older men — ScienceDaily  –  Read More

Restless legs syndrome – other useful resources

  • Restless legs syndrome: Causes, treatments, and home remedies –   Read More
  • Iron reduces parasomnias in children with restless legs | Medpage Today –  Read More
  • Restless Legs Syndrome: symptoms and treatment | Live Science –  Read More
  • Restless Leg Syndrome and nerve cells –  Read More
  • What to eat if you have restless legs syndrome – Health Essentials from Cleveland Clinic-  Read More
  • Varicose veins doctors help hundreds of seniors in New York struggling with varicose veins through minimally-invasive procedures – Read More
  • Restless arms syndrome: prevalence, impact, and management strategies | NDT –  Read More
  • How to handle restless legs syndrome – Consumer Reports –  Read More
  • Restless legs syndrome: a new practice guideline – Clinical Advisor –  Read More
  • Restless legs syndrome: how to stop twitching legs | Wellness | US News –  Read More
  • Cureus | Treatment of leg veins for restless leg syndrome: a retrospective review –  Read More
  • Local team gives new life to restless legs syndrome treatment – Carle Foundation Newsroom –  Read More
  • Treatment options for idiopathic restless legs syndrome – touchNEUROLOGY –  Read More
  • How is RLS treated? | Otsuka Pharmaceutical Co., Ltd. –  Read More
  • Differential diagnosis and treatment of restless legs syndrome: a literature review –  Read More
  • Restless legs syndrome: learning to live with it –  Read More
  • Exploring sleep-related movement disorders – Neurology Advisor –  Read More

Medical equipment and devices for restless legs syndrome

  • Study reviews medical device treatments for restless legs syndrome – Sleep Review –  Read More
  • Tech could deliver a good night’s rest – Winnipeg Free Press –  Read More
  • This device uses radio waves to track how you’re sleeping | Innovation | Smithsonian Magazine –  Read More
  • medi USA launches new drug-free treatment for restless legs syndrome (RLS) –  Read More
  • Relaxis, the first medical device approved in U.S. for restless legs syndrome | Medgadget –  Read More
  • Stimulators implanted in the lower spine can help up to 1 in 15 Brits with restless leg syndrome –  Read More
  • Sequential compression devices for treatment of restless legs syndrome – Full Text View – –  Read More

Guidance for Comprehensive List of Leg & Foot Related Pain from Leg Pain Guide.

(During this stressful period of COVID-19, here’s our research review of the uncommon and unusual symptoms of corona virus disease.)





















Restless Leg Syndrome – RLS treatment, doctor, medicine and hospital resources for

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Australia – Sydney – New South Wales, Melbourne – Victoria, Brisbane – Queensland, Perth – Western Australia, Adelaide – South Australia, Gold Coast–Tweed Heads – Queensland/New South Wales, Newcastle–Maitland – New South Wales, Canberra–Queanbeyan – Australian Capital Territory/New South Wales, Sunshine Coast – Queensland, Wollongong – New South Wales, Hobart – Tasmania, Geelong – Victoria, Townsville – Queensland, Cairns – Queensland, Darwin – Northern Territory, Toowoomba – Queensland, Ballarat – Victoria, Bendigo – Victoria, Albury–Wodonga – New South Wales/Victoria, Launceston – Tasmania

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India – Mumbai (Bombay)– Maharashtra, New Delhi – Delhi, Bangalore (Bengaluru) – Karnataka, Hyderabad – Telangana, Ahmedabad – Gujarat, Chennai (Madras) – Tamil Nadu, Kolkata (Calcutta) – West Bengal, Surat – Gujarat, Pune – Maharashtra, Jaipur – Rajasthan, Lucknow – Uttar Pradesh, Kanpur – Uttar Pradesh, Nagpur – Maharashtra, Visakhapatnam – Andhra Pradesh, Indore – Madhya Pradesh, Thane – Maharashtra, Bhopal – Madhya Pradesh, Pimpri-Chinchwad – Maharashtra, Patna – Bihar, Vadodara – Gujarat, Ghaziabad – Uttar Pradesh, Ludhiana – Punjab, Coimbatore – Tamil Nadu, Agra – Uttar Pradesh, Madurai – Tamil Nadu

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South Africa – Cape Town – Western Cape, Johannesburg , – Gauteng, Durban – KwaZulu-Natal, Pretoria – Gauteng, Port Elizabeth – Eastern Cape, Bloemfontein – Free State, Nelspruit – Mpumalanga, Kimberley – Northern Cape, Polokwane – Limpopo, Pietermaritzburg – KwaZulu-Natal


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Ireland – Dublin  – Leinster, Cork  – Munster, Dún Laoghaire  – Leinster, Limerick – Munster, Galway – Connaught, Tallaght  – Leinster, Waterford  – Munster, Swords – Leinster, Drogheda – Leinster, Dundalk – Leinster

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Top 20 Web Sites & Guides for Health, Illnesses & Diseases

Bupa – BUPA UKBUPA Global Cleveland Clinic – Link
Cedars-Sinai – Link Centers for Disease Control & Prevention (CDC) – Link – Link eMedicine Health – Link
Everyday Health – Link HealthLine – Link
John Hopkins Medicine Health Library – Link LiveStrong – Link
Mayo Clinic – Link Medical News Today – Link
MedicineNet – Link MedlinePlus – Link
MedScape – Link Merck Manuals – Link
NHS UK – Link NIH – Link
Patient Info – Link WebMD – Link